Acute Renal Failure
Acute kidney injury (AKI) is the sudden loss of kidney function. Kidneys clean wastes from the blood and maintain fluid levels in the body.
Problems can happen:
- Before blood enters the kidneys
- Inside the kidneys (most common)
- When urine leaves the kidneys and moves toward the bladder
|Anatomy of the Kidney|
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AKI has many causes:
- Blood is blocked from going into the kidneys because of:
- Problems with blood vessels
- Blood loss
- Excessive fluid loss—dehydration
- Problems inside the kidney cause tissue death because of:
- Problems after surgery
- Blood clots
- Medicine side effects
- Kidney stones
- Enlarged prostate
AKI is most common in older adults and females. Your chances are also higher if you have:
- High blood pressure
- Kidney, liver, or heart disease
- Bleeding from the stomach or intestines
- Taken certain medicines
- Used illegal drugs
- Problems after surgery or a hospital stay
- Overused certain nonsteroidal anti-inflammatory drugs (NSAIDs)
- Used angiotensin converting enzyme (ACE) inhibitors
- Blockages, which can happen with benign prostatic hyperplasia or a bladder tumor
Care depends on the cause of AKI and how serious it is. Care may involve:
- Stopping or changing medicines causing harm to your kidneys
- Dietary changes that limit how much protein you eat
- IV fluids
- Dialysis—a machine works for your kidneys by filtering your blood
- Caring for problems such as kidney stones or infections
- Kidney transplant
- Dialysis—a machine used to filter waste from the blood
This content is reviewed regularly and is updated when new and relevant evidence is made available. This information is neither intended nor implied to be a substitute for professional medical advice. Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with questions regarding a medical condition.
Edits to original content made by Denver Health.
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a (AKI; Acute Kidney Failure; Acute Renal Failure; Acute Renal Insufficiency)
National Institute of Diabetes and Digestive and Kidney Diseases https//www.niddk.nih.gov
National Kidney Foundation https://www.kidney.org
Health Canada https://www.canada.ca
The Kidney Foundation of Canada https://www.kidney.ca
Acute kidney injury. EBSCO DynaMed website. Available at: http://www.dynamed.com/topics/dmp~AN~T566508/Acute-kidney-injury . Updated April 26, 2018. Accessed May 31, 2018.
Acute kidney injury (AKI). Merck Manual Professional Version website. Available at: https://www.merckmanuals.com/professional/genitourinary-disorders/acute-kidney-injury/acute-kidney-injury-aki. Updated December 2017. Accessed May 31, 2018.
Kidney failure. National Institute of Diabetes and Digestive and Kidney Diseases website. Available at: https://www.niddk.nih.gov/health-information/kidney-disease/kidney-failure. Accessed May 31, 2018.
Rahman M, Shad F, Smith MC. Acute kidney injury: a guide to diagnosis and management. Am Fam Physician. 2012;86(7):631-639.